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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109546Generated: October 30, 2026

4-Ethylbenzene-1-sulfonyl chloride → 2'-(4-Ethylphenylsulfonylaminomethyl)biphenyl-2-carboxylic acid phenethylamide

https://huagongshe.com/reaction/2109546

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Ethylbenzene-1-sulfonyl chlorideHCID 570959—
Reactant2'-(Aminomethyl)-N-(2-phenylethyl)[1,1'-biphenyl]-2-carboxamideHCID 15509384—
ReactantHCID 68968595HCID 68968595—
Product2'-(4-Ethylphenylsulfonylaminomethyl)biphenyl-2-carboxylic acid phenethylamideHCID 9870530—

Reaction Steps

From 0.61 mmol of 2′-aminomethylbiphenyl-2-carboxylic acid -phenethylamide (precursor 5a) and 4-ethylphenylsulfonyl chloride, according to the general working procedure 250 mg of 2′-(4-ethylphenylsulfonyl-aminomethyl)biphenyl-2-carboxylic acid phenethylamide were obtained;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514582B2
Source datasetuspto-grants-2009_04
ORD IDord-3bef3afe6cb045bd8d2de0c2959ef7be
Source noteuspto-grants-2009_04