HRID2109549

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2734258

3-Fluorobenzenesulfonyl chloride

C6H4ClFO2S

HCID15509385

未命名化合物

结构：NC(c1ccccc1-c1ccccc1C(=O)NCc1ccccc1)S(=O)(=O)c1cccc(F)c1

HCID68971718

未命名化合物

PRODUCTS

生成物

结构：O=C(NCc1ccccc1)c1ccccc1-c1ccccc1CNS(=O)(=O)c1cccc(F)c1

HCID9847725

未命名化合物

PROCEDURE

实验过程

From 0.28 mmol of 2′-aminomethylbiphenyl-2-carboxylic acid benzylamide (precursor 5b) and 3-fluorophenylsulfonyl chloride, according to the general working procedure 112 mg of 2′-(3-fluorophenylsulfonyl-aminomethyl)biphenyl-2-carboxylic acid benzylamide were obtained;

WORKUP

后处理

customwere obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-03586c491d9d4ee08664e7dd86dc5f82
来源数据集: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07514582B2
来源说明: uspto-grants-2009_04

反应 SMILES

[CH2:1]([NH:8][C:9]([C:11]1[C:12]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[CH2:23][NH2:24])=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:25][C:26]1[CH:27]=[C:28]([S:32](Cl)(=[O:34])=[O:33])[CH:29]=[CH:30][CH:31]=1.C(NC(C1C(C2C=CC=CC=2C(S(C2C=CC=C(F)C=2)(=O)=O)N)=CC=CC=1)=O)C1C=CC=CC=1>>[CH2:1]([NH:8][C:9]([C:11]1[C:12]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[CH2:23][NH:24][S:32]([C:28]2[CH:29]=[CH:30][CH:31]=[C:26]([F:25])[CH:27]=2)(=[O:34])=[O:33])=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1