HCID 86621483, compound → HCID 86760843, compound

HRID 2109958Notes

Reaction equation

HRID 2109958 reaction equation
[CH3:1][O:2][S:3]([O-:6])(=[O:5])=[O:4].[CH3:7][N+:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH2:14][CH2:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N+:23]([O-])=O.[H][H]>O.[Pd]>[CH3:1][O:2][S:3]([O-:6])(=[O:5])=[O:4].[NH2:23][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=1[O:16][CH2:15][CH2:14][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][N+:8]=1[CH3:7]

Participants

5

Reactant 2

HCID 86621483HCID 86621483, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 86760843HCID 86760843, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 962WaterSolvent

Procedure

3.7 g (10 mmol) of the compound from Step 3.2 was hydrogenated in 25 mL of water in the presence of 0.3 g of Pd/C (10%) under 9 bar of hydrogen pressure. After 2 hours, the catalyst was filtered off, and the solution obtained was directly subjected to further reaction.

Workup

  1. filtrationthe catalyst was filtered off
  2. customthe solution obtained
  3. customwas directly subjected to further reaction

Sources & evidence

ORD record
ord-6958194011a746a2ab011163945d77af
Source dataset
uspto-grants-2009_04
Patent number
US07517367B2

Reaction notes

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