Dimethyl Sulfate → HCID 86069942, compound

Participants

Reaction Steps

4.4 g (21 mol) of the compound from Step 12.1 was dissolved in 50 mL of ethyl acetate and to the resulting mixture was added 2.65 g (21 mmol) of dimethyl sulfate over a period of 5 min with agitation. A precipitate was formed as a result of a slightly exothermic reaction. The mixture was allowed to agitate for an additional hour after which it was suction-filtered. The filter cake was then washed with ethyl acetate and dried at 40° C. under vacuum which gave 6.5 g (92% of the theoretical) of colorless crystals.

Provenance & Evidence