反应详情

4.4 g (21 mol) of the compound from Step 12.1 was dissolved in 50 mL of ethyl acetate and to the resulting mixture was added 2.65 g (21 mmol) of dimethyl sulfate over a period of 5 min with agitation. A precipitate was formed as a result of a slightly exothermic reaction. The mixture was allowed to agitate for an additional hour after which it was suction-filtered. The filter cake was then washed with ethyl acetate and dried at 40° C. under vacuum which gave 6.5 g (92% of the theoretical) of colorless crystals.

1. customA precipitate was formed as
2. customa result of a slightly exothermic reaction
3. filtrationwas suction-filtered
4. washThe filter cake was then washed with ethyl acetate
5. customdried at 40° C. under vacuum which
6. customgave 6.5 g (92% of the theoretical) of colorless crystals