HCID 86069942, compound → HCID 86069945, compound

HRID 2109972Notes

Reaction equation

HRID 2109972 reaction equation
[CH3:1][O:2][S:3]([O-:6])(=[O:5])=[O:4].[CH3:7][N+:8]([CH3:22])([CH3:21])[CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][N:13]=1.[H][H]>O.[Pd]>[CH3:1][O:2][S:3]([O-:6])(=[O:5])=[O:4].[NH2:18][C:15]1[CH:16]=[CH:17][C:12]([O:11][CH2:10][CH2:9][N+:8]([CH3:22])([CH3:21])[CH3:7])=[N:13][CH:14]=1

Participants

5

Reactant 2

HCID 86069942HCID 86069942, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 86069945HCID 86069945, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 962WaterSolvent

Procedure

4.0 g (12 mmol) of the compound from Step 12.2 in 80 mL of water was hydrogenated in the presence of 0.4 g of Pd/C (10%) under 9 bar of hydrogen pressure. After 3 hours the catalyst was filtered off and the water was removed in a rotary evaporator.

Workup

  1. filtrationAfter 3 hours the catalyst was filtered off
  2. customthe water was removed in a rotary evaporator

Sources & evidence

ORD record
ord-6afdf3c9030f4b3aaac4b41695338fed
Source dataset
uspto-grants-2009_04
Patent number
US07517367B2

Reaction notes

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