Hydrochloric Acid → HCID 136383508, compound

Participants

Reaction Steps

A mixture of the product of Example 45 (4 mg, 0.0059 mmol) and 4 N HCl in dioxane (0.25 mL) was stirred at room temperature for 2 h. After which, the solution was concentrated in vacuo to afford the title compound as a white solid (3.5 mg, 97%). 1H NMR (300 MHz, DMSO-d6) δ ppm 0.57-0.74 (m, 6H), 0.79-0.94 (m, 1H), 1.19-1.39 (m, 2H), 1.75-1.90 (m, 1H), 1.92-2.12 (m, 1H), 3.05 (s, 3H), 7.42-7.66 (m, 5H), 7.88-7.97 (m, 2H), 8.10 (d, J=7.72 Hz, 1H), 9.39 (s, 1H), 10.15 (s, 1H), 14.19 (s, 1H); MS m/z 575.7 (M+H)+.

Provenance & Evidence