反应详情

5-[(E)-2-Phenylvinyl]-3-[4-(trifluoromethyl)phenyl]-1H-pyrazole (1.56 g, 4.96 mmol) was dissolved in a mixed solvent of tetrahydrofuran (30 mL) and ethanol (30 mL), 10% palladium-carbon (50% water-containing product, 500 mg) was added, and the mixture was stirred at room temperature under an atmospheric hydrogen atmosphere for 2 hr. The catalyst was filtered off and the filtrate was concentrated to give the title compound (880 mg, yield 56%) as colorless crystals. MS: m/z 317 (MH+).

1. additionwas added
2. filtrationThe catalyst was filtered off
3. concentrationthe filtrate was concentrated