HCID 23157275, compound → HCID 23160005, compound

Participants

Reaction Steps

A mixture of methyl 4-[(3-tert-butyl-5-{[4-(methoxycarbonyl)benzyl]oxy}-1H-pyrazol-1-yl)methyl]benzoate (6.90 g, 15.8 mmol), 10% palladium-carbon (50% water-containing product, 0.35 g) and tetrahydrofuran (50 mL) was stirred overnight at room temperature under a hydrogen atmosphere. The catalyst was filtered off and the obtained filtrate was concentrated to give the title compound (3.70 g, yield 81%) as colorless crystals. melting point 161-162° C.

Provenance & Evidence