Dimethylformamide → 4-{4-Nitro-3-[(2-phenoxy-acetyl)-(4-trifluoromethoxy-benzyl)-amino]-phenyl}-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16]([NH:23][C:24]([CH2:25][O:26][c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)=[O:33])[c:17]([N+:20](=[O:21])[O-:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[F:34][C:35]([O:36][c:37]1[cH:38][cH:39][c:40]([CH2:41][Br:42])[cH:43][cH:44]1)([F:45])[F:46].[O:47]=[CH:48][N:49]([CH3:50])[CH3:51]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16]([N:23]([C:24]([CH2:25][O:26][c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)=[O:33])[CH2:41][c:40]3[cH:39][cH:38][c:37]([O:36][C:35]([F:34])([F:45])[F:46])[cH:44][cH:43]3)[c:17]([N+:20](=[O:21])[O-:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-61ea5eeb6e984f2280380f8f55ffcac5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…