HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-piperidone → HCID 59003394, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-piperidone | HCID 19220 | — |
| Reactant | 1-Bromo-4-(trifluoromethoxy)benzene | HCID 521008 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 59003394 | HCID 59003394 | — |
Reaction Steps
This compound is prepared according to the procedure described in step A of Preparation 8.5, starting with 20 g of 1-bromo-4-(trifluoromethoxy)benzene in 300 ml of THF, 89.3 ml of a 1.6M solution of n-butyllithium in hexane and 24.1 ml of 1-benzyl-4-piperidinone in 50 ml of THF. 18.5 g of the expected product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07521449B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-82b1bcd997d0412cb4738990d893cbda |
| Source note | uspto-grants-2009_04 |