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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2111636Generated: November 1, 2026

HCID 86603558, compound → HCID 68919313, compound

https://huagongshe.com/reaction/2111636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86603558HCID 86603558—
SolventPropylamineHCID 7852—
ProductHCID 68919313HCID 68919313169.6%

Reaction Steps

5,6-Dimethyl-2-(3-pyridyl)-3-mesyloxyethylisoindolin-1-one (0.11 g, 0.31 mmol) was stirred in n-propylamine (3 ml) at 25° C. for 6 hrs. The reaction solution was concentrated under reduced pressure, and the residue was purified by silica gel chromatography (chloroform:methanol=15:1) to give 85 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07521451B2
Source datasetuspto-grants-2009_04
ORD IDord-813d2aca12dd4d15904ece5d11bfa43d
Source noteuspto-grants-2009_04