HCID 86606184, compound → HCID 57640192, compound

Participants

Reaction Steps

830 mg (2.136 mmol) 8-dibenzylamino-2-(2-fluoro-ethyl)-3,4-dihydro-2H-isoquinolin-1-one are dissolved in 50 ml of methanol and combined with 80 mg palladium hydroxide. The reaction mixture is stirred for 48 h at ambient temperature and 4.5 bar H2 pressure. Then the catalyst is filtered off and the solvent is eliminated in vacuo.

Provenance & Evidence