HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178487895, compound → 2-[2-(4-amino-3-methoxy-phenyl)-1H-imidazol-4-yl]-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178487895 | HCID 178487895 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[2-(4-amino-3-methoxy-phenyl)-1H-imidazol-4-yl]-ethanol | HCID 178487894 | — |
Reaction Steps
0.144 g (0.547 mmol) 2-[2-(3-methoxy-4-nitro-phenyl)-1H-imidazol-4-yl]-ethanol are dissolved in 100 ml of methanol and combined with 0.08 g (5%) palladium on charcoal. The reaction mixture is hydrogenated for 16 h at 20° C. and 4 bar H2 pressure. The palladium on charcoal is suction filtered and the methanol is eliminated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07521457B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-2ff643f36d0e4b78b674535d5239491f |
| Source note | uspto-grants-2009_04 |