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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2112102Generated: November 1, 2026

HCID 178487895, compound → 2-[2-(4-amino-3-methoxy-phenyl)-1H-imidazol-4-yl]-ethanol

https://huagongshe.com/reaction/2112102

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178487895HCID 178487895—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-[2-(4-amino-3-methoxy-phenyl)-1H-imidazol-4-yl]-ethanolHCID 178487894—

Reaction Steps

0.144 g (0.547 mmol) 2-[2-(3-methoxy-4-nitro-phenyl)-1H-imidazol-4-yl]-ethanol are dissolved in 100 ml of methanol and combined with 0.08 g (5%) palladium on charcoal. The reaction mixture is hydrogenated for 16 h at 20° C. and 4 bar H2 pressure. The palladium on charcoal is suction filtered and the methanol is eliminated in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07521457B2
Source datasetuspto-grants-2009_04
ORD IDord-2ff643f36d0e4b78b674535d5239491f
Source noteuspto-grants-2009_04