Acetone → benzyl N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)carbamate

HRID 211213Notes

Reaction equation

HRID 211213 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:44][C:45](=[O:46])[CH3:47].[ClH:43].[F:1][c:2]1[c:3]([NH:10][C:11]([O:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)=[O:20])[cH:4][c:5]([OH:9])[c:6]([Cl:8])[cH:7]1.[K+:25].[K+:26].[c:27]1([CH3:28])[cH:29][cH:30][c:31]([S:32]([O:33][CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41]2)(=[O:34])=[O:35])[cH:36][cH:42]1>>[F:1][c:2]1[c:3]([NH:10][C:11]([O:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)=[O:20])[cH:4][c:5]([O:9][CH:37]2[CH2:38][CH2:39][CH2:40][CH2:41]2)[c:6]([Cl:8])[cH:7]1

Participants

7

Reactant 6

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 317685Cyclopentyl 4-methylbenzene-1-sulfonateHCID 19374488benzyl N-(4-chloro-2-fluoro-5-hydroxyphenyl)carbamate

Product 1

HCID 19374482benzyl N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)carbamate

Sources & evidence

ORD record
ord-72cfb584aae0437685a482709bcbbd88
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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