L-Aspartic Acid → Calcium (2S)-2-aminobutanedioate--hydrogen chloride (1/1/1)

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Reaction Steps

1010 l of demineralized water are heated to 60° C., after which 509 kg of L-aspartic acid are added while stirring. 142 kg of calcium hydroxide are added in the form of a powder in portions to the resulting dispersion while stirring continuously. The temperature rises further and the solution becomes clear after about 1 h. A solution of 281 kg of calcium chloride dihydrate in 325 l of water (35% strength solution) is added to this solution. The concentration based on the complex is adjusted to 30% with water. This is followed by filtration and spray drying in the manner described in Example 1.

Provenance & Evidence