HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Naphthalenesulfonyl chloride → 1-(1-Naphthylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Naphthalenesulfonyl chloride | HCID 66560 | — |
| Reactant | tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate | HCID 22015386 | — |
| Product | 1-(1-Naphthylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride | HCID 10113364 | — |
Reaction Steps
The title compound was prepared according 4-(4-boc-piperazinyl)-indole and naphthylsulfonylchloride according to Method 3: 1H NMR (270 MHz DMSO-d6) δ 9.03 (br, 1H), 8.63 (d, J=8 Hz, 1H), 8.43 (d, J=8 Hz, 1H, 8.34 (d, J=8 Hz, 1H), 8.15-8.05 (m, 2H), 7.80-7.65 (m, 3H), 7.41 (d, J=8 Hz, 1H) 7.18 (t, J=8 Hz, 1H), 6.93 (d, J=5 Hz, 1H), 6.74 (d, J=8 Hz, 1H), 3.30-3.20 (m, 8H); MS (ESI+) for m/z 392 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524839B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-0884af8d9902454f8e1ad11e9117ce5e |
| Source note | uspto-grants-2009_04 |