HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 4-(1-Piperazinyl)-1-(2-methylbenzenesulfonyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 4-Bromo-1-(2-methyl-benzenesulfonyl)-1H-indole | HCID 22015334 | — |
| Product | 4-(1-Piperazinyl)-1-(2-methylbenzenesulfonyl)-1H-indole | HCID 10157299 | — |
Reaction Steps
The title compound was prepared from 4-bromo-1-(2-methyl-benzenesulfonyl)-1H-indole and piperazine according to Method 1 to give 25 mg (12%) of a white solid: 1NMR (CD3OD) δ 7.91-6.79 (m, 9H), 3.49-3.30 (m, 8H), 2.48 (s, 3H); MS (ESI) 356.1 (M+H)+; Purity (HPLC) >95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524839B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-3c27076aadde4d0f94908982eda5cc26 |
| Source note | uspto-grants-2009_04 |