2-Chlorobenzaldehyde → (2-Amino-5-bromo-4-methoxyphenyl)-(2-chlorophenyl)-methanone

HRID 2112469Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[Br:10][C:11]1[CH:17]=[CH:16][C:14]([NH2:15])=[CH:13][C:12]=1[O:18][CH3:19]>>[NH2:15][C:14]1[CH:13]=[C:12]([O:18][CH3:19])[C:11]([Br:10])=[CH:17][C:16]=1[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[Cl:1])=[O:5]

Participants

Reactant 2

HCID 69962-Chlorobenzaldehyde

HCID 70182544-Bromo-3-methoxyaniline

Product 1

HCID 57642384(2-Amino-5-bromo-4-methoxyphenyl)-(2-chlorophenyl)-methanone

Procedure

(2-amino-5-bromo-4-methoxyphenyl)-(2-chlorophenyl)-methanone (Xd) was prepared by reacting 2-chlorobenzaldehyde with 0.086 moles of 4-bromo-3-methoxy aniline in a manner analogous to Example 1. MH+/Z=340.

Sources & evidence

ORD record: ord-65b548123b3249f68a50fb626490f355
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07524840B2

Reaction notes

Loading…