HRID211247

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID923

Sodium ion

Na+

HCID962

Water

H2O

HCID6228

Dimethylformamide

C3H7NO

HCID166653

Hydride

H-

HCID9994433

TERT-BUTYL 4-(HYDROXYMETHYL)-4-PHENYLPIPERIDINE-1-CARBOXYLATE

C17H25NO3

HCID58993492

未命名化合物

PRODUCTS

产物

HCID58993687

tert-Butyl 4-((3-(5-methyl-1H-tetrazol-1-yl)-5-(trifluoromethyl)benzyloxy)methyl)-4-phenylpiperidine-1-carboxylate

C27H32F3N5O3

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-c7c4b8a932ef480cabb5011edc94901e
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应SMILES

[Br:1][CH2:2][c:3]1[cH:4][c:5](-[n:13]2[n:14][n:15][n:16][c:17]2[CH3:18])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[H-:40].[Na+:41].[OH2:47].[OH:19][CH2:20][C:21]1([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]1>>[CH2:2]([c:3]1[cH:4][c:5](-[n:13]2[n:14][n:15][n:16][c:17]2[CH3:18])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)[O:19][CH2:20][C:21]1([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]1