2-Chlorobenzaldehyde → (2-Amino-4-chloro-5-methoxyphenyl)(2-chlorophenyl)-methanone

HRID 2112472Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[NH2:14]>>[NH2:14][C:13]1[CH:12]=[C:11]([Cl:10])[C:17]([O:18][CH3:19])=[CH:16][C:15]=1[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[Cl:1])=[O:5]

Participants

Reactant 2

HCID 69962-Chlorobenzaldehyde

HCID 214413-Chloro-4-methoxyaniline

Product 1

HCID 57642385(2-Amino-4-chloro-5-methoxyphenyl)(2-chlorophenyl)-methanone

Procedure

(2-amino-4-chloro-5-methoxyphenyl)-(2-chlorophenyl)-methanone (Xy) was prepared by reacting 2-chlorobenzaldehyde with 0.019 moles of 3-chloro-4-methoxy aniline in a manner analogous to Example 1. MH+/Z=296.

Sources & evidence

ORD record: ord-e4b601179dd7457ca06002ce87bff4c5
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07524840B2

Reaction notes

Loading…