2-Chlorobenzaldehyde → (2-Amino-5-methoxy-4-phenylphenyl)-(2-chlorophenyl)-methanone

HRID 2112479Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[CH3:10][O:11][C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[CH:14][C:13]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[NH2:16][C:15]1[CH:14]=[C:13]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:12]([O:11][CH3:10])=[CH:18][C:17]=1[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[Cl:1])=[O:5]

Participants

Reactant 2

HCID 69962-Chlorobenzaldehyde

HCID 1235414-Methoxy-3-phenylaniline

Product 1

HCID 57642374(2-Amino-5-methoxy-4-phenylphenyl)-(2-chlorophenyl)-methanone

Procedure

(2-amino-5-methoxy-4-phenylphenyl)-(2-chlorophenyl)-methanone (Xff) was prepared by reacting 2-chlorobenzaldehyde with 0.0226 moles of 4-methoxy-3-phenyl aniline in a manner analogous to the Example 1. MH+/Z=338.

Sources & evidence

ORD record: ord-8ef2c8860d8b481c92dccdabed638a15
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07524840B2

Reaction notes

Loading…