2-Chlorobenzaldehyde → HCID 57642367, compound

HRID 2112482Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[CH:10]([O:13][C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][C:20]=1[O:21][CH3:22])[NH2:17])([CH3:12])[CH3:11]>>[NH2:17][C:16]1[CH:15]=[C:14]([O:13][CH:10]([CH3:11])[CH3:12])[C:20]([O:21][CH3:22])=[CH:19][C:18]=1[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[Cl:1])=[O:5]

Participants

Reactant 2

HCID 69962-Chlorobenzaldehyde

HCID 16785912HCID 16785912, compound

Product 1

HCID 57642367HCID 57642367, compound

Procedure

(2-amino-5-methoxy-4-(1-methylethoxy)phenyl)-(2-chlorophenyl)-methanone (Xii) was prepared by reacting 2-chlorobenzaldehyde with 0.0252 moles of 3-isopropoxy-4-methoxy aniline in a manner analogous to Example 1. MH+/Z=320.

Sources & evidence

ORD record: ord-750b47d9beb44a3485afea218298549c
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07524840B2

Reaction notes

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