2-Chlorobenzaldehyde → (2-Amino-4-methoxy-5-(2-methoxyethoxy)phenyl)-(2-chlorophenyl)-methanone

HRID 2112484Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:16]=[CH:17][C:18]=1[O:19][CH2:20][CH2:21][O:22][CH3:23])[NH2:15]>>[NH2:15][C:14]1[CH:13]=[C:12]([O:11][CH3:10])[C:18]([O:19][CH2:20][CH2:21][O:22][CH3:23])=[CH:17][C:16]=1[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[Cl:1])=[O:5]

Participants

Reactant 2

HCID 69962-Chlorobenzaldehyde

HCID 621107783-Methoxy-4-(2-methoxyethoxy)aniline

Product 1

HCID 57642366(2-Amino-4-methoxy-5-(2-methoxyethoxy)phenyl)-(2-chlorophenyl)-methanone

Procedure

(2-amino-4-methoxy-5-(2-methoxyethoxy)phenyl)-(2-chlorophenyl)-methanone (Xkk) was prepared by reacting 2-chlorobenzaldehyde with 0.0242 moles of 3-methoxy-4-(2-methoxyethoxy) aniline in a manner analogous to Example 1. MH+/Z=336.

Sources & evidence

ORD record: ord-3addf868c17d46e1a4276ad16cb4e806
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07524840B2

Reaction notes

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