Diisobutylaluminumhydride → HCID 178486510, compound

Participants

Role	Name	HCID	Charge
Reactant	Diisobutylaluminumhydride	HCID 21225700	—
Reactant	HCID 57642319	HCID 57642319	—
Reactant	1-Allyl-5-chloro-3-methyl-1H-pyrazol-4-amine	HCID 57642344	—
Reactant	HCID 178456655	HCID 178456655	—
Product	HCID 178486510	HCID 178486510	—

Reaction Steps

1,2-dihydro-7,8-dimethoxy-5-(2-methoxyphenyl)-3-methyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVaa) was prepared by reacting 0.0023 moles of (2-amino-4,5-dimethoxyphenyl)-(2-methoxyphenyl)-methanone (Xaa) with 4-amino-5-chloro-3-methyl-1-(2-propenyl)-1H-pyrazole (XIII), and subsequent dealkylation of the intermediate, 1,2-dihydro-7,8-dimethoxy-5-(2-methoxyphenyl)-3-methyl-1-(2-propenyl)-pyrazolo[3,4-b][1,4]benzodiazepine (XIVaa) with diisobutylaluminum hydride in a manner analogous to Example 72. MH+/Z=365.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07524840B2
Source dataset	uspto-grants-2009_04
ORD ID	ord-cf544af3723d454c83e7f288e4c16bad
Source note	uspto-grants-2009_04