Dichloromethane → (4-chloro-benzyl)-[6-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridazin-3-yl]-amine

HRID 211287Notes

Reaction equation

HRID 211287 reaction equation
[C:1]([O:2][C:3](=[O:4])[n:8]1[cH:9][c:10]([CH2:17][c:18]2[n:19][n:20][c:21]([NH:24][CH2:25][c:26]3[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]3)[cH:22][cH:23]2)[c:11]2[c:12]1[n:13][cH:14][cH:15][cH:16]2)([CH3:5])([CH3:6])[CH3:7].[Cl:40][CH2:41][Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[nH:8]1[cH:9][c:10]([CH2:17][c:18]2[n:19][n:20][c:21]([NH:24][CH2:25][c:26]3[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]3)[cH:22][cH:23]2)[c:11]2[c:12]1[n:13][cH:14][cH:15][cH:16]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 576192483-[6-(4-Chloro-benzylamino)-pyridazin-3-ylmethyl]-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester

Product 1

HCID 57619452(4-chloro-benzyl)-[6-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridazin-3-yl]-amine

Sources & evidence

ORD record
ord-17da436f7c004729b1150ef66ea64170
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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