Water → HCID 86605133, compound

Participants

Reaction Steps

7-(2-Butynyl)-2,6-dichloro-9-methyl-7,9-dihydropurin-8-one (compound 1e) (100 mg) was dissolved in acetonitrile (1.5 mL). Piperidin-3-yl-carbamic acid t-butyl ester (compound 25b) (111 mg) and triethylamine (77 μL) were then added to this solution. After stirring the reaction solution at room temperature for 24 hours, water (6 mL) was added. After stirring this reaction solution at room temperature for 30 minutes, the precipitate was filtered, and the white solid obtained was washed with water and hexane to give the title compound (88 mg).

Provenance & Evidence