HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allylamine → Allyl-(3-nitropyridin-4-yl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allylamine | HCID 7853 | — |
| Reactant | 4-Ethoxy-3-nitropyridine--hydrogen chloride (1/1) | HCID 12407497 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Allyl-(3-nitropyridin-4-yl)amine | HCID 23070628 | — |
Reaction Steps
Allyl amine (40 mL) was added to a solution of 4-ethoxy-3-nitropyridine hydrochloride [CAS No. 94602-04-7] (18.0 g) in ethanol (400 mL), and this was heated under reflux for eight hours. The reaction solution was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography. The fraction eluted by ethyl acetate-hexane (1:1) gave the title compound (13.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524847B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-b1284af7c671471987f95206590abe28 |
| Source note | uspto-grants-2009_04 |