反应详情

温度

60 °C

A slurry of the product of Step 1 (0.268 g, 0.754 mmol) in dimethylacetamide (10 mL) was treated with ethylamine (2 mL, 30.6 mmol) then heated to 60° C. in a sealed tube for 16 h. The precipitate was filtered, washed with dimethylacetamide and then water, to give title compound as a solid; m.p. 317-321° C. ACPI-MS Found: [M+H]+=355.

1. filtrationThe precipitate was filtered
2. washwashed with dimethylacetamide