Veratrylamine → HCID 68839477, compound

HRID 2112953Notes

Reaction equation

HRID 2112953 reaction equation
C(O[C:4]([C:6]1[N:11]2[N:12]=[C:13]([NH:15][C:16]([NH:18][CH2:19][CH3:20])=[O:17])[N:14]=[C:10]2[CH:9]=[C:8]([Br:21])[CH:7]=1)=[O:5])C.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][C:31]=1[O:32][CH3:33])[CH2:27][NH2:28]>C(O)C>[CH3:22][O:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][C:31]=1[O:32][CH3:33])[CH2:27][NH:28][C:4]([C:6]1[N:11]2[N:12]=[C:13]([NH:15][C:16]([NH:18][CH2:19][CH3:20])=[O:17])[N:14]=[C:10]2[CH:9]=[C:8]([Br:21])[CH:7]=1)=[O:5]

Participants

4

Reactant 2

HCID 79832VeratrylamineHCID 576430687-Bromo-2-(3-ethyl-ureido)-[1,2,4]triazolo[1,5-a]pyridine-5-carboxylic acid ethyl ester

Product 1

HCID 68839477HCID 68839477, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

7-Bromo-2-(3-ethyl-ureido)-[1,2,4]triazolo[1,5-a]pyridine-5-carboxylic acid ethyl ester, which may be prepared as in Example 6, (253 mg, 0.714 mmol) and 3,4-dimethoxybenzylamine (0.55 mL) were taken up in ethanol (4.0 mL). After 24 h the precipitate was removed by filtration and washed with ethanol to afford 7-bromo-2-(3-ethyl-ureido)-[1,2,4]triazolo[1,5-a]pyridine-5-carboxylic acid 3,4-dimethoxy-benzylamide MS (APCI+): m/z 478.4 (M+H).

Workup

  1. customAfter 24 h the precipitate was removed by filtration
  2. washwashed with ethanol

Sources & evidence

ORD record
ord-4c102188abff4dca8b9bfebb2a793c35
Source dataset
uspto-grants-2009_04
Patent number
US07524860B2

Reaction notes

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