HCID 68835224, compound → HCID 68839833, compound

Participants

Reaction Steps

The product of Step 2, 4-[2-(3-ethyl-ureido)-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-5-yl]-piperazine-1-carboxylic acid tert-butyl ester (0.52 g, 1.1 mmol) was suspended in CH2Cl2 (10 mL) Trifluoroacetic acid (5 ml) was added and the resulting solution was stirred at rt for 30 minutes. The reaction mixture was diluted with toluene and solvent was evaporated. The residue was purified by column chromatography on silica gel (0-10% MeOH in CH2Cl2 containing 1% NEt3 as eluant) to afford the target compound as a solid. MS (APCI+) 366 (M+1).

Provenance & Evidence