Ethylamine → HCID 68573520, compound

HRID 2112980Notes

Reaction equation

HRID 2112980 reaction equation
C(O[C:4]([C:6]1[N:11]2[N:12]=[C:13]([NH2:15])[N:14]=[C:10]2[CH:9]=[C:8]([C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)[CH:7]=1)=[O:5])C.[CH2:22]([NH2:24])[CH3:23]>C1COCC1>[CH2:22]([NH:24][C:4]([C:6]1[N:11]2[N:12]=[C:13]([NH2:15])[N:14]=[C:10]2[CH:9]=[C:8]([C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)[CH:7]=1)=[O:5])[CH3:23]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 57643066HCID 57643066, compound

Product 1

HCID 68573520HCID 68573520, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A suspension of the product of Step 1 (0.69 g, 2.45 mmol) in 2 M solution of ethylamine in THF (15 mL) was allowed to stir at room temperature for 2 days. The solid precipitate was filtered to give 2-amino-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-5-carboxylic acid ethyl amide as a solid. MS m/z 283 (M+H+).

Workup

  1. filtrationThe solid precipitate was filtered

Sources & evidence

ORD record
ord-b3834d3df62e4e74b2e3ea03e902852d
Source dataset
uspto-grants-2009_04
Patent number
US07524860B2

Reaction notes

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