4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine dihydrobromide → N-(2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-[6-methyl-2-oxo-3-(3-trifluoromethyl-phenylmethanesulfonylamino)-2H-pyridin-1-yl]-acetamide

Participants

Role	Name	HCID	Charge
Reactant	4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine dihydrobromide	HCID 13670689	—
Reactant	2-[6-methyl-2-oxo-3-({[3-(trifluoromethyl)benzyl]sulfonyl}amino)-1(2H)-pyridinyl]acetic acid	HCID 57643372	—
Product	N-(2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-[6-methyl-2-oxo-3-(3-trifluoromethyl-phenylmethanesulfonylamino)-2H-pyridin-1-yl]-acetamide	HCID 44339443	—

Reaction Steps

The title compound was prepared from 2-[6-methyl-2-oxo-3-({[3-(trifluoromethyl)benzyl]sulfonyl}amino)-1(2H)-pyridinyl]acetic acid and 4,5,6,7-tetrahydro-1,3-benzothiazol-2,6-diamine dihydrobromide using the procedure of EXAMPLE 1 (STEP 6), and was obtained as a white solid compound.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07524871B2
Source dataset	uspto-grants-2009_04
ORD ID	ord-fa0fc867077a43799b03899a252bfc84
Source note	uspto-grants-2009_04