1-Butanesulfonyl chloride → HCID 69037715, compound

HRID 2113057Notes

Reaction equation

HRID 2113057 reaction equation
[NH2:1][C:2]1[C:3](=[O:17])[N:4]([CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[C:5]([CH3:8])=[CH:6][CH:7]=1.[CH2:18]([S:22](Cl)(=[O:24])=[O:23])[CH2:19][CH2:20][CH3:21]>>[CH2:18]([S:22]([NH:1][C:2]1[C:3](=[O:17])[N:4]([CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[C:5]([CH3:8])=[CH:6][CH:7]=1)(=[O:24])=[O:23])[CH2:19][CH2:20][CH3:21]

Participants

3

Reactant 2

HCID 754301-Butanesulfonyl chlorideHCID 104901153-Amino-6-methyl-1-(tert-butoxycarbonylmethyl)-2-pyridinone

Product 1

HCID 69037715HCID 69037715, compound

Procedure

The title compound was prepared from tert-butyl 2-[3-amino-6-methyl-2-oxo-1(2H)-pyridinyl]acetate (EXAMPLE 1, STEP 1-3), and 1-butanesulfonyl chloride using the procedure of EXAMPLE 9 (STEP 2). The product was recrystallized from ethylacetate to give a white crystalline solid compound.

Workup

  1. customThe product was recrystallized from ethylacetate
  2. customto give a white crystalline solid compound

Sources & evidence

ORD record
ord-847a9db6abed4dd0aa234b477f940c29
Source dataset
uspto-grants-2009_04
Patent number
US07524871B2

Reaction notes

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