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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2113148Generated: November 4, 2026

Phenol → 5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-methyl-2,3-dihydro-benzofuran-2-carboxylic acid

https://huagongshe.com/reaction/2113148

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
Reactant5-Hydroxy-2-methyl-2,3-dihydro-benzofuran-2-carboxylic acid methyl esterHCID 11356233—
ReactantBenzene, 2-chloro-1-(3-iodopropoxy)-4-(trifluoromethoxy)-HCID 69053655—
Product5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-methyl-2,3-dihydro-benzofuran-2-carboxylic acidHCID 10478763—

Reaction Steps

The title compound was prepared following the general procedure described in Example 1, Step 4, using the the intermediate prepared in Example 1, Step 1 as the phenol and the iodide prepared in Step 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524882B2
Source datasetuspto-grants-2009_04
ORD IDord-7d944248f43a4831870ba54082f3bf6b
Source noteuspto-grants-2009_04