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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2113153Generated: October 30, 2026

2-Ethyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester → 5-{3-[2-Chloro-4-(1,1-dimethyl-propyl)-phenoxy]-propoxy}-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid

https://huagongshe.com/reaction/2113153

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl esterHCID 11160373—
Reactant2-Chloro-1-(3-iodopropoxy)-4-(2-methylbutan-2-YL)benzeneHCID 69053642—
Product5-{3-[2-Chloro-4-(1,1-dimethyl-propyl)-phenoxy]-propoxy}-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acidHCID 10388902—

Reaction Steps

The title compound was prepared following the general procedure described in Example 1, Step 4 employing the phenol prepared in Example 4, Step 1 and the iodide prepared in Step 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524882B2
Source datasetuspto-grants-2009_04
ORD IDord-8e98604b74c24357ac195c20eccf83d0
Source noteuspto-grants-2009_04