HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester → (2S)-5-{3-[2-Chloro-4-(2,2-dimethyl-propyl)-phenoxy]-propoxy}-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester | HCID 11160373 | — |
| Reactant | 2-Chloro-4-(2,2-dimethylpropyl)-1-(3-iodopropoxy)benzene | HCID 69049858 | — |
| Product | (2S)-5-{3-[2-Chloro-4-(2,2-dimethyl-propyl)-phenoxy]-propoxy}-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid | HCID 10343562 | — |
Reaction Steps
The title compound was prepared following the general procedure described in Example 1, Step 4 employing the chiral phenol prepared in Example 10, Step 2 and the iodide prepared in Step 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524882B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-0c9b1cdfdc764fbb8e30af6667541ae8 |
| Source note | uspto-grants-2009_04 |