HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-6-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester → 6-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-6-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester | HCID 11379051 | — |
| Reactant | Benzene, 2-chloro-1-(3-iodopropoxy)-4-(trifluoromethoxy)- | HCID 69053655 | — |
| Product | 6-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid | HCID 11385663 | — |
Reaction Steps
The title compound was prepared following the general procedure described in Example 1, Step 4, employing the phenol prepared in Step 2 and the iodide prepared in Example 3, Step 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524882B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-dfa1ec8a14574874afc6c224d1b2752e |
| Source note | uspto-grants-2009_04 |