HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-tert-Butyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester → (R)-2-tert-Butyl-5-[2-(2-chloro-4-trifluoromethoxy-phenoxy)-ethoxy]-2,3-dihydro-benzofuran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-tert-Butyl-5-hydroxy-2,3-dihydro-benzofuran-2-carboxylic acid methyl ester | HCID 11459363 | — |
| Reactant | 2-[2-Chloro-4-(trifluoromethoxy)phenoxy]ethyl iodide | HCID 57643416 | — |
| Product | (R)-2-tert-Butyl-5-[2-(2-chloro-4-trifluoromethoxy-phenoxy)-ethoxy]-2,3-dihydro-benzofuran-2-carboxylic acid | HCID 11282914 | — |
Reaction Steps
The title compound was prepared following the general procedure described in Example 1, Step 4, employing the phenol prepared in Example 21, Step 1 and the iodide prepared in Example 23, Step 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524882B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-e9c9724a98264ee8a97cc311c18c65a3 |
| Source note | uspto-grants-2009_04 |