Potassium Carbonate → (Phenylmethyl)hydrazine

HRID 2113222Notes

Reaction equation

HRID 2113222 reaction equation
C([O-])([O-])=O.[K+].[K+].Cl.Cl.[CH2:9]([NH:16][NH2:17])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>CCOCC>[CH2:9]([NH:16][NH2:17])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 146540Benzylhydrazine dihydrochloride

Product 1

HCID 11157(Phenylmethyl)hydrazine

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

An excess of K2CO3 (7.5 g) was added to a solution of benzylhydrazine dihydrochloride (7.00 g, 35.9 mmol) in Et2O (100 mL). The mixture was stirred at ambient temperature for 2 hrs and the reaction was quenched with water (20 mL). The organic layer was washed with water and brine and dried with anhydrous Na2SO4, then filtered and concentrated in vacuo to yield benzylhydrazine Compound 1d (4.17 g, 34.2 mmol).

Workup

  1. customthe reaction was quenched with water (20 mL)
  2. washThe organic layer was washed with water and brine
  3. dry with materialdried with anhydrous Na2SO4
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-2a2f007f8cf74f7aa87c59854024ddff
Source dataset
uspto-grants-2009_04
Patent number
US07524964B2

Reaction notes

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