Potassium Carbonate → HCID 69106680, compound

Participants

Reaction Steps

In analogy to example 5a, 2,3-difluoro-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 16 h at 90° C. After aqueous workup and crystallization from Ethyl acetate/diisopropylether the title compound was obtained as an off-white solid (yield: 28%). 1H-NMR (300 MHz, DMSO): δ=2.19 (d, J=0.9 Hz, 3H), 7.26 (s with fine splitting, 1H), 7.71-7.89 (m, 1H), 7.86-7.94 (m, 3H)

Provenance & Evidence