m-Chloroperbenzoic acid → 4-(4-Fluoro-phenyl)-pyridine 1-oxide

HRID 2113544Notes

Reaction equation

HRID 2113544 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[F:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=2)=[CH:15][CH:14]=1>C(Cl)(Cl)Cl>[F:12][C:13]1[CH:14]=[CH:15][C:16]([C:19]2[CH:20]=[CH:21][N+:22]([O-:9])=[CH:23][CH:24]=2)=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 155443714-(4-Fluorophenyl)pyridine

Product 1

HCID 187002504-(4-Fluoro-phenyl)-pyridine 1-oxide

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
0 °C

Procedure

3.5 g (10.2 mmol) of meta-chloroperbenzoic acid are added to a solution of 1.18 g (6.81 mmol) of 4-(4-fluorophenyl)pyridine in 5 mL of chloroform cooled to 0° C. The suspension is stirred for 30 minutes.

Sources & evidence

ORD record
ord-91873448255c456fb82bfc36d4f840d8
Source dataset
uspto-grants-2008_10
Patent number
US07432269B2

Reaction notes

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