HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-Chloro-4-(4-fluorophenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 4-(4-Fluoro-phenyl)-pyridine 1-oxide | HCID 18700250 | — |
| Product | 2-Chloro-4-(4-fluorophenyl)pyridine | HCID 23120730 | — |
Reaction Steps
A mixture of 0.9 g (4.8 mmol) of 4-(4-fluorophenyl)pyridine-1-oxide and 10 mL of phosphoryl chloride is heated at reflux overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07432269B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-921ad7bfd8214392960609e59c5cf2cb |
| Source note | uspto-grants-2008_10 |