Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 68884629 | HCID 68884629 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 10423239 | HCID 10423239 | — |
Reaction Steps
Compound 102 was dissolved in 5 mL of methanol and cooled to 0° C. A solution of freshly prepared NaOMe in methanol was added, and the solution was warmed to room temperature and stirred overnight. TLC (70:30 hexanes/ethyl acetate) showed no starting material. The reaction was acidified with Dowex resin, filtered, and concentrated to a white solid. The compound 103 was recrystallized from ethyl acetate/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07432292B2 |
|---|
| Source dataset | uspto-grants-2008_10 |
|---|
| ORD ID | ord-d4e0831033e04dd3a30239819d1344e8 |
|---|
| Source note | uspto-grants-2008_10 |
|---|
