HCID 2745164, compound → HCID 69203229, compound

Participants

Reaction Steps

N-(4′-{[(Cyclopropylmethyl)amino]carbonyl}-6-methyl-1,1′-biphenyl-3-yl)-1-ethyl-3-(thiophen-2-yl)pyrazole-5- carboxamide was prepared from 5′-amino-N-(cyclopropylmethyl)-2′-methyl-1,1′-biphenyl-4-carboxamide and 1-ethyl-3-(thiophen-2-yl)pyrazole-5- carboxylic acid using method D. NMR; δH CDCl3 8.02,(1H, b), 7.86-7.83,(3H, m), 7.57,(1H, dd), 7.47,(1H, d), 7.40,(2H, d), 7.34,(1H, m), 7.30-7.26,(3H, m), 7.07,(1H, m), 4.63,(2H, q), 3.35,(2H, m), 2.24,(3H, s), 1.08,(1H, m), 0.58,(2H, m), 0.30,(2H, m). LCMS: retention time 3.81 min, MH+485.

Provenance & Evidence