Cyclopropanecarboxylic acid → HCID 44578402, compound

Participants

Reaction Steps

N-(4′-{[(Cyclopropylmethyl)amino]carbonyl}-6-methyl-1,1′-biphenyl-3-yl)cyclopropanecarboxamide was prepared from 5′-amino-N-(cyclopropylmethyl)-2′-methyl-1,1′-biphenyl-4-carboxamide and cyclopropanecarboxylic acid using method D. NMR; δH [2H6]—DMSO 10.18,(1H, s), 8.60,(1H, t), 7.91,(2H, d), 7.50-7.47,(2H, m), 7.40,(2H, d), 7.21,(1H, d), 3.16,(2H, t), 2.16,(3H, s), 1.74,(1H, m),1.04,(1H, m), 0.77-0.75,(4H, m), 0.43,(2H, m), 0.23,(2H, m). LCMS: retention time 3.19 min, MH+349.

Provenance & Evidence