HCID 57503457, compound → HCID 23641307, compound

Participants

Reaction Steps

2-(2-{3-Benzyloxy-4-[(4′-trifluoromethyl-biphenyl-2-carbonyl)amino]phenyl}acetoxymethyl)-2-phenylmalonic acid diethyl ester (Reference Example 2-4) (0.310 g) was dissolved in methanol, and palladium carbon (0.04 g) was added thereto. The mixture was hydrogenated at normal pressure for 2 hours. The reaction solution was filtered through a Celite, and the filtrate was concentrated to give the title compound as a colorless non-crystalline substance (0.245 g).

Provenance & Evidence