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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2114332Generated: October 27, 2026

1-([1,1'-Biphenyl]-4-yl)-N-methyl-2-(pyrrolidin-1-yl)ethan-1-amine → HCID 46847713, compound

https://huagongshe.com/reaction/2114332

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-([1,1'-Biphenyl]-4-yl)-N-methyl-2-(pyrrolidin-1-yl)ethan-1-amineHCID 2756716—
ReactantHCID 57418650HCID 57418650—
Reactant[1-(4-Biphenylyl)-2-(4-morpholinyl)ethyl]methylamineHCID 57425536—
ReactantHCID 57457147HCID 57457147—
ProductHCID 46847713HCID 4684771358%

Reaction Steps

The title compound was prepared according to the procedure described in example 11 replacing N-(3,4-dichlorophenyl)-N-methylglycine with (6,7-dibromo-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetic acid, and [1-(4-biphenylyl)-2-(1-pyrrolidinyl)ethyl]methylamine with the product from step b) above to give the title compound (52 mg, 58%). MS (ES) m/e 643 [M+H]+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07432258B2
Source datasetuspto-grants-2008_10
ORD IDord-92a802837be845e9aaf935a82d69dd5f
Source noteuspto-grants-2008_10