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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2114580Generated: October 29, 2026

Potassium Hydroxide → HCID 178462354, compound

https://huagongshe.com/reaction/2114580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant2,4-DifluorophenolHCID 123051—
ReactantHCID 178462356HCID 178462356—
ProductHCID 178462354HCID 178462354—

Reaction Steps

(R)-1-(3-Cyclopentyl-6-methylsulfonyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-propan-2-ol was treated with 2,4-difluorophenol in the presence of KOH using the procedure of step 6 of Example 4 to afford 0.56 mg of (R)-1-[3-Cyclopentyl-6-(2,4-difluoro-phenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino]-propan-2-ol. Mass Spec. M+H=390.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435731B2
Source datasetuspto-grants-2008_10
ORD IDord-26fead1285b24c9bbc6b5c0360a33992
Source noteuspto-grants-2008_10