Pyridine → HCID 17961872, compound

HRID 2114768Notes

Reaction equation

HRID 2114768 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[C:10]1[N:11]([CH3:30])[C:12](=[O:29])[C:13]([O:20][C:21](=[O:28])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:14]([C:16]([O:18][CH3:19])=[O:17])[N:15]=1.N1C=CC=CC=1.[C:37]1([C:43](Cl)=[O:44])[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1>C1COCC1>[C:43]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[C:10]1[N:11]([CH3:30])[C:12](=[O:29])[C:13]([O:20][C:21](=[O:28])[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[C:14]([C:16]([O:18][CH3:19])=[O:17])[N:15]=1)(=[O:44])[C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1

Participants

5

Reactant 3

HCID 1049PyridineHCID 7412Benzoyl chlorideHCID 17961875HCID 17961875, compound

Product 1

HCID 17961872HCID 17961872, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

THF was added to the crude product of Step 1, followed by pyridine (2 eq.) and PhCOCl (1 eq.). After being stirred at room temperature overnight, the reaction mixture was evaporated to give the crude title product.

Workup

  1. customthe reaction mixture was evaporated

Sources & evidence

ORD record
ord-bdea349dcebc4fa6b2011a2b6057c476
Source dataset
uspto-grants-2008_10
Patent number
US07435734B2

Reaction notes

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